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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 12.73
Human Site: S165 Identified Species: 20
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 S165 M P W P E P Q S P R V L P N G
Chimpanzee Pan troglodytes XP_510301 627 67581 T144 M F L S T A A T A P P S S S K
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 S165 M P W P E P Q S P R V L P N G
Dog Lupus familis XP_544614 968 105825 S452 M P W P E P Q S P R V L P N G
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 P166 P W P E P Q S P Q A L P N G M
Rat Rattus norvegicus Q62829 544 60692 K61 G G G D K T N K K K E K E R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 A156 L G A R P G E A R P N G L V G
Chicken Gallus gallus XP_426393 667 74767 D165 P D Y K P R L D G Q S H P N G
Frog Xenopus laevis NP_001082100 650 73749 P160 H R A V P Q Q P R G Q E P S N
Zebra Danio Brachydanio rerio XP_001919719 693 77347 T165 M G L K K S V T L Q P N G I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 A156 P P R V R R V A N V P P S V P
Honey Bee Apis mellifera XP_001122147 624 70155 T141 G Q E M S S N T N Q I Q S Y T
Nematode Worm Caenorhab. elegans Q17850 572 63863 T89 D P K T G E F T G M P E A W A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 D316 I K R N S Q D D K R A S S S S
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 K314 R V P G M L R K K S G F S G F
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 0 0 N.A. 6.6 20 13.3 6.6 N.A. 6.6 0 6.6 N.A.
P-Site Similarity: 100 20 100 100 N.A. 6.6 13.3 N.A. 26.6 33.3 20 26.6 N.A. 13.3 20 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 0 0 7 7 14 7 7 7 0 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 7 0 0 7 14 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 7 20 7 7 0 0 0 7 14 7 0 0 % E
% Phe: 0 7 0 0 0 0 7 0 0 0 0 7 0 0 7 % F
% Gly: 14 20 7 7 7 7 0 0 14 7 7 7 7 14 34 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % I
% Lys: 0 7 7 14 14 0 0 14 20 7 0 7 0 0 7 % K
% Leu: 7 0 14 0 0 7 7 0 7 0 7 20 7 0 7 % L
% Met: 34 0 0 7 7 0 0 0 0 7 0 0 0 0 7 % M
% Asn: 0 0 0 7 0 0 14 0 14 0 7 7 7 27 7 % N
% Pro: 20 34 14 20 27 20 0 14 20 14 27 14 34 0 14 % P
% Gln: 0 7 0 0 0 20 27 0 7 20 7 7 0 0 0 % Q
% Arg: 7 7 14 7 7 14 7 0 14 27 0 0 0 7 0 % R
% Ser: 0 0 0 7 14 14 7 20 0 7 7 14 34 20 7 % S
% Thr: 0 0 0 7 7 7 0 27 0 0 0 0 0 0 7 % T
% Val: 0 7 0 14 0 0 14 0 0 7 20 0 0 14 0 % V
% Trp: 0 7 20 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _